Dyslipidemia; Helicobacter pylori infected patients

To determine the frequency of dyslipidemia in Helicobacter pylori infected patients. This cross sectional descriptive study of six months study was conducted at Liaquat University Hospital Hyderabad from 01-03-2012 to 31-08- 2012. All the patients between 19 to 60 years of age present with symptoms of dyspepsia, bloating or epigastric discomfort for more than 01 week duration were admitted and evaluated for Helicobacter pylori infection. Thereafter the positive cases [Helicobacter pylori infected patients] were further evaluated for dyslipidemia. During six month study period, total 144 patients [95 males and 49 females] with Helicobacter pylori infection were evaluated for dyslipidemia [lipid profile]. Majority of patients were from urban areas 110/144 [76%]. The mean +/- SD for age of patients with Helicobacter pylori infection was 35.94 +/- 10.77. The mean age +/- SD of dyslipidemic patient was 32.62 +/- 6.52. The dyslipidemia was identified in 87 [60.4%] patients, of which 51[58.6%] were males and 36[41.4%] were females. Regarding the pattern of dyslipidemia, ten [11.4%] patients had raised serum triglycerides level, twenty eight [32%] had raised LDL-C level, twenty six [28.9%] had raised serum cholesterol level, seven [8.7%] had low HDL-C level and sixteen [18.3%] had mixed dyslipidemia. The mean +/- SD of hypertriglyceridemia, [Upwards Arrow] HDL-C, [Upwards Arrow] LDL-C and hypercholesterolemia in dyslipidemic Helicobacter pylori infected was 280.72 +/- 22.85, 24.21 +/- 2.63, 180.63 +/- 12.98 and 285.21 +/- 23.63 respectively. The H. pylori infected patients are prone to acquire dyslipidemia, therefore the present study observed 60.4% prevalence of dyslipidemia with male predominance [58.6%]

Serum iron level; patients with Helicobacter pylori infection

To determine the serum iron level in Helicobacter pylori infected patients. This cross sectional descriptive study was conducted at Liaquat University Hospital [a tertiary care teaching hospital] Hyderabad from July 2013 to December 2013. All the patients with history of presented with acute abdominal pain, dyspepsia, bloating and epigastric discomfort were evaluated for Helicobacter pylori infection by serology. Thereafter the Helicobacter pylori positive individuals were further evaluated for serum iron level. The data was collected, saved and analyzed in SPSS version 11.00. During six month study period total one hundred patients of H. pylori infection was recruited, of which sixty three [63%] were males and thirty seven were females. Sixty six [66%] patients belonged to urban areas while thirty four [34%] were rural population. The mean age +/- SD for overall population was 37.35 +/- 14.0 where as the mean age +/- SD of male and female population was 38.88 +/- 6.77 and 35.67 +/- 8.87 respectively. The serum iron was low in 68% Helicobacter pylori infected patients, of which 48 were males and 20 were females [p=0.02]. The overall mean +/- SD for serum iron level in study population was 49.17 +/- 37.86 mmol/L whereas the mean +/- SD of serum iron for male and female Helicobacter pylori infected population was 42.69 +/- 34.15 and 60.18 +/- 41.66 [p=0.03]. An association was identified between Helicobacter pylori and iron deficiency